HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boronic acid, (4-ethylphenyl)- → N-(5-(4-ethylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boronic acid, (4-ethylphenyl)- | HCID 2734352 | — |
| Reactant | N-(5-bromo-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide | HCID 67280716 | — |
| Product | N-(5-(4-ethylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide | HCID 56961394 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 39, using N45-bromo-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-nicotinamide (example G) and B-(4-ethylphenyl)-boronic acid (CAN 63139-21-9) as starting materials; LC-MS (UV peak area/ESI) 100%, 402.1409 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-53b8289a7610419894c112d52b783984 |
| Source note | uspto-grants-2013_04 |