(4-Chloro-3-methylphenyl)boronic acid → HCID 67280473, compound

HRID 1958180Notes

Reaction equation

HRID 1958180 reaction equation
Br[C:2]1[CH:3]=[C:4]([NH2:13])[CH:5]=[N:6][C:7]=1[O:8][CH2:9][CH2:10][O:11][CH3:12].[Cl:14][C:15]1[CH:20]=[CH:19][C:18](B(O)O)=[CH:17][C:16]=1[CH3:24]>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([C:2]2[CH:3]=[C:4]([NH2:13])[CH:5]=[N:6][C:7]=2[O:8][CH2:9][CH2:10][O:11][CH3:12])=[CH:17][C:16]=1[CH3:24]

Participants

3

Reactant 2

HCID 3786632(4-Chloro-3-methylphenyl)boronic acidHCID 59352839HCID 59352839, compound

Product 1

HCID 67280473HCID 67280473, compound

Procedure

The title compound was synthesized in analogy to Example E, using 5-bromo-6-(2-methoxy-ethoxy)-pyridin-3-ylamine (example 69 b) and B-(4-chloro-3-methylphenyl)-boronic acid (CAN 161950-10-3) as starting materials; GC/MS (FID/EI): 100%, 292 (M)+.

Sources & evidence

ORD record
ord-ab9cdde96025401cb310a60ec5e85344
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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