2-Pyrazinecarboxylic acid → N-(5-(4-chlorophenyl)-6-cyclobutoxypyridin-3-yl)pyrazine-2-carboxamide
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:19])[CH:11]=[N:12][C:13]=2[O:14][CH:15]2[CH2:18][CH2:17][CH2:16]2)=[CH:4][CH:3]=1.[N:20]1[CH:25]=[CH:24][N:23]=[CH:22][C:21]=1[C:26](O)=[O:27]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH:19][C:26]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][N:20]=3)=[O:27])[CH:11]=[N:12][C:13]=2[O:14][CH:15]2[CH2:18][CH2:17][CH2:16]2)=[CH:4][CH:3]=1参加物
3
実験手順
The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine (example 78 d) and 2-pyrazinecarboxylic acid (CAN 98-97-5) as starting materials; MS (EI) 381.2(M+H)+.
出典と根拠
- ORDレコード
- ord-d1ac54e363a74f3dafb615021d921c02
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08410107B2
反応ノート
読み込み中…