化工社化工社 化学情報印刷レポート · 研究参考用
(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → (+/-)-1-Oxiranylmethyl-4-(3-phenyl-propyl)-piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate | HCID 286836 | — |
| 反応物 | 1-(3-Phenylpropyl)piperazine | HCID 796534 | — |
| 生成物 | (+/-)-1-Oxiranylmethyl-4-(3-phenyl-propyl)-piperazine | HCID 17810519 | 80% |
反応手順
The same method as employed in the preparation of Intermediate 1 but starting from 1-(3-phenylpropyl)-piperazine and 3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after Biotage chromatography the title compound as a yellow oil in a 80% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08410110B2 |
| 出典データセット | uspto-grants-2013_04 |
| ORD ID | ord-d886676127f948e8827648f620700b6d |
| 出典メモ | uspto-grants-2013_04 |