HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid → 4-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(3-fluoro-phenyl)-imidazo[1,2-a]pyrimidin-7-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid | HCID 58446796 | — |
| Reactant | 2-(3-Fluorophenyl)imidazo[1,2-c]pyrimidin-7-amine | HCID 67391146 | — |
| Product | 4-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(3-fluoro-phenyl)-imidazo[1,2-a]pyrimidin-7-yl]-amide | HCID 67384093 | — |
Reaction Steps
The title compound was prepared in analogy to example 82 from 2-(3-fluorophenyl)imidazo[1,2-c]pyrimidin-7-amine (100 mg) and 4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid (100 mg, 440 μmol). Yellow solid (76 mg, 39%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410117B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-27557bb3c13b48efa23ba3ea21a48328 |
| Source note | uspto-grants-2013_04 |