HCID 58446878, compound → HCID 53468454, compound

HRID 1958357Notes

Reaction equation

HRID 1958357 reaction equation
[NH2:1][C:2]1[N:7]=[CH:6][N:5]2[CH:8]=[C:9]([C:11]3[CH:12]=[C:13]([CH:20]=[CH:21][CH:22]=3)[O:14][CH2:15][C:16]([O:18][CH3:19])=[O:17])[N:10]=[C:4]2[CH:3]=1.[CH2:23]([N:25]([CH3:37])[C:26]([C:28]1[CH:29]=[N:30][N:31]([CH3:36])[C:32]=1[C:33](O)=[O:34])=[O:27])[CH3:24]>>[CH3:19][O:18][C:16](=[O:17])[CH2:15][O:14][C:13]1[CH:20]=[CH:21][CH:22]=[C:11]([C:9]2[N:10]=[C:6]3[N:7]=[C:2]([NH:1][C:33]([C:32]4[N:31]([CH3:36])[N:30]=[CH:29][C:28]=4[C:26](=[O:27])[N:25]([CH2:23][CH3:24])[CH3:37])=[O:34])[CH:3]=[CH:4][N:5]3[CH:8]=2)[CH:12]=1

Participants

3

Reactant 2

HCID 58446878HCID 58446878, compoundHCID 67391949HCID 67391949, compound

Product 1

HCID 53468454HCID 53468454, compound

Procedure

The title compound was prepared in analogy to example 82 from methyl 2-(3-(7-aminoimidazo[1,2-c]pyrimidin-2-yl)phenoxy)acetate (105 mg, 352 μmol) and 4-(ethyl(methyl)carbamoyl)-1-methyl-1H-pyrazole-5-carboxylic acid (74.3 mg, 352 μmol). Light yellow solid (30 mg, 16%). MS (m/z)=492.2 [M+H+].

Sources & evidence

ORD record
ord-cd83b7ac71d64cc4ae4d06f7bfa779c7
Source dataset
uspto-grants-2013_04
Patent number
US08410117B2

Reaction notes

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