HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 44626000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-1-propanol | HCID 12313 | — |
| Reactant | HCID 67184799 | HCID 67184799 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 44626000 | HCID 44626000 | 54.3% |
Reaction Conditions
| Temperature | 110 °C |
|---|
Reaction Steps
1 g of the compound obtained in stage 4B), 0.376 g of potassium carbonate and 0.223 g of 3-chloropropan-1-ol are added to 6 ml of DMF. The reaction medium is heated at 110° C. for 3 hours. The reaction medium is subsequently poured onto distilled water and the compound obtained is extracted with ethyl acetate. The organic phase is dried and evaporated. After purifying by chromatography on silica (eluent: CH2Cl2-MeOH (gradient from 0% to 4%)), 0.6 g of the expected compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410137B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-4539de32c66f411c9cd1f8a945121207 |
| Source note | uspto-grants-2013_04 |