HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 67185456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 4-Phenylpiperidine-4-carboxamide monohydrochloride | HCID 3017129 | — |
| Reactant | HCID 67184742 | HCID 67184742 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67185456 | HCID 67185456 | 87% |
Reaction Steps
0.5 g of the compound obtained in stage 16G), 0.25 g of 4-phenylpiperidine-4-carboxamide hydrochloride, 0.43 ml of Et3N and 0.36 g of TBTU are added to 10 ml of CH2Cl2 and then reaction is allowed to take place at AT for 2 hours. After concentrating to dryness, taking up the residue in a water/ether mixture and filtering, 0.6 g of the expected compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410137B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-342172f1def84165931dd712f0eebe46 |
| Source note | uspto-grants-2013_04 |