反应详情

According to the method described in example S11, aminocarnitine (40 mg) was reacted with 4-isocyanatobiphenyl to yield the title compound as a white solid (25.7 mg). 1H NMR (400 MHz, CD3OD): δ=7.58-7.45 (m, 6H), 7.39 (t, J=7.60 Hz, 2H), 7.28 (t, J=7.20, 1H), 4.66 (br s, 1H), 3.74 (dd, J=9.20 Hz, 13.20 Hz, 1H), 3.54 (d, 13.6 Hz, 1H), 3.23 (s, 9H), 2.65-2.55 (m, 2H), 1.98 (s, 3H). MS ESI [M+H]+, calcd for [C20H25N3O3+H]+: 356.4 found m/z 356.2 (100).