HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-t-Amylbenzenesulphonyl chloride → (R)-benzyl 4-(dimethylamino)-3-(4-pentylphenylsulfonamido)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-t-Amylbenzenesulphonyl chloride | HCID 144625 | — |
| Reactant | (R)-benzyl 3-amino-4-(dimethylamino)butanoate | HCID 46223508 | — |
| Product | (R)-benzyl 4-(dimethylamino)-3-(4-pentylphenylsulfonamido)butanoate | HCID 86641219 | 25% |
Reaction Steps
According to the method described in example S20a, (R)-benzyl 3-amino-4-(dimethylamino)butanoate (27 mg, 0.086 mmol) was reacted with 4-pentylbenzene-1-sulfonyl chloride to yield the title compound as a white solid (9 mg, 25%). MS ESI 447.3 [M+H]+, calcd for [C24H34N2O4S+H]+ 447.22
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410150B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-bc589176c98746ae801ce22d1ee2b18d |
| Source note | uspto-grants-2013_04 |