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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1958727Generated: October 31, 2026

N-Dodecylaniline → (R)-benzyl 4-(dimethylamino)-3-(3-dodecyl-3-phenylureido)butanoate

https://huagongshe.com/reaction/1958727

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-DodecylanilineHCID 76362—
ReactantTriphosgeneHCID 94429—
Reactant(R)-benzyl 3-amino-4-(dimethylamino)butanoateHCID 46223508—
Product(R)-benzyl 4-(dimethylamino)-3-(3-dodecyl-3-phenylureido)butanoateHCID 86641224—

Reaction Steps

According to the method described in example S40a, (R)-benzyl 3-amino-4-(dimethylamino)butanoate is reacted with of triphosgene and N-dodecylaniline to yield (R)-benzyl 4-(dimethylamino)-3-(3-dodecyl-3-phenylureido)butanoate. According to the methods described in example S40b,c the preceding benzyl ester is converted to the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410150B2
Source datasetuspto-grants-2013_04
ORD IDord-35357cac0cd24c408c79d5faa4d6547b
Source noteuspto-grants-2013_04