HCID 59294360, compound → HCID 25064258, compound

Participants

Reaction Steps

According to the method described in example S64, (R)-3-(3-(phenylethynyl)-benzamido)-4-(trimethylammonio)butanoate was treated with 10% Pd/C under hydrogen and the product purified to give the title compound as a white powder (7.2 mg, 89%). 1H NMR (400 MHz, D2O) δ 7.41 (d, 1H, J=8 Hz), 7.34 (s, 1H), 7.07 (t, 1H, J=8 Hz), 7.02-6.90 (m, 4H), 6.86 (d, 2H, J=8 Hz), 4.76 (m, 1H), 3.60-3.54 (m, 1H), 3.41 (d, 1H, J=13.2 Hz), 3.00 (s, 9H), 2.61 (br, 4H), 2.41-2.28 (m, 2H); MS ESI 369.2 [M+H]+, calcd for [C22H28N2O3+H]+ 369.22.

Provenance & Evidence