HRID1958738

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

结构：CCCCCCCCCCc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)CN(C)C)cc1

HCID86641229

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)C[N+](C)(C)C)cc1.[I-]

HCID68742977

未命名化合物

PROCEDURE

实验过程

According to the method described in example S75b, (R)-benzyl 3-(4-decylphenylsulfonamido)-4-(dimethylamino)butanoate was reacted with methyl iodide to give the title compound as a white solid (quantitative). MS ESI 531.4 [M+H]+, calcd for [C30H46N2O4S+H]+ 531.3

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8c29602ca83343eca4ef9bc854260ef3
来源数据集: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08410150B2
来源说明: uspto-grants-2013_04

反应 SMILES

[CH2:1]([C:11]1[CH:16]=[CH:15][C:14]([S:17]([NH:20][C@@H:21]([CH2:33][N:34]([CH3:36])[CH3:35])[CH2:22][C:23]([O:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:24])(=[O:19])=[O:18])=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH3:37][I:38]>>[I-:38].[CH2:26]([O:25][C:23](=[O:24])[CH2:22][C@@H:21]([NH:20][S:17]([C:14]1[CH:15]=[CH:16][C:11]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])=[CH:12][CH:13]=1)(=[O:19])=[O:18])[CH2:33][N+:34]([CH3:37])([CH3:36])[CH3:35])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1