Potassium Fluoride → 2-Ethynyl-5-hexylthiophene

Participants

Reaction Steps

According to the method of S117b, ((5-hexylthiophen-2-yl)ethynyl)trimethylsilane (1 g, 3.7 mmol) was reacted with potassium fluoride (429 mg, 7.4 mmol) to give the title compound as a yellow oil following silica gel purification (hexane) (500 mg, 70%). 1H NMR (400 MHz, CDCl3) δ 7.10 (d, 1H, J=3.6 Hz), 6.64 (d, 1H, J=3.6 Hz), 2.78 (t, 2H, J=7.2 Hz) 1.68-1.55 (m, 2H), 1.36-1.28 (m, 6H), 0.89 (t, 3H, J=6.4 Hz).

Provenance & Evidence