HCID 25066344, compound → HCID 25066342, compound

Participants

Reaction Steps

According to the method described in example S64, (R)-3-(5-((5-hexylthiophen-2-yl)ethynyl)furan-2-carboxamido)-4-(trimethylammonio)butanoate was treated with 10% Pd/C under hydrogen and the product purified to give the title compound as a white powder (14.6 mg, 72%), 1H NMR (400 MHz, D2O) δ 6.85 (br, 1H), 6.32 (br, 1H), 6.21 (br, 1H), 5.65 (br, 1H), 3.64 (m, 1H), 3.41-3.38 (m, 2H), 3.01 (s, 9H), 2.72 (br, 2H), 2.61 (br, 2H), 2.38-2.23 (m, 4H); 1.34 (br, 2H), 1.07 (br, 6H), 0.68 (br, 3H); MS ESI [M+H]+, calcd for [C24H36N2O4S+H]+ 449.25; found m/z 449.3.

Provenance & Evidence