HCID 25066338, compound → HCID 59294362, compound

Participants

Reaction Steps

According to the method described in example S64, (R)-3-(5-((4-pentylphenyl)ethynyl)furan-2-carboxamido)-4-(trimethylammonio)butanoate was treated with 10% Pd/C under hydrogen overnight and the product purified to give the title compound as a white powder (16.5 mg, 48%). 1H NMR (400 MHz, D2O) δ 6.86 (d, 2H, J=8.2 Hz), 6.75 (d, 2H, J=7.6 Hz), 4.60-4.53 (m, 1H), 4.08-4.01 (m, 1H), 3.61-3.36 (m, 3H), 3.02 (s, 9H), 2.45-2.32 (m, 6H), 1.87-1.50 (m, 5H), 1.35-1.27 (m, 2H), 1.25-1.05 (m, 5H), 0.60-0.55 (m, 3H); MS ESI [M+H]+, calcd for [C25H40N2O4+H]+ 433.31; found m/z 433.3.

Provenance & Evidence