Potassium Fluoride → HCID 86641235, compound

Participants

Reaction Steps

According to the method of Example S117b, ((3-(heptyloxy)phenyl)ethynyl)trimethyl silane (575 mg, 2.1 mmol) was reacted with potassium fluoride (429 mg, 7.4 mmol) to give the title compound as a clear oil following silica gel purification (hexane) (390 mg, 93%). 1H NMR (400 MHz, CDCl3) 1H NMR (400 MHz, CDCl3) δ 7.22 (t, 1H, J=7.6 Hz), 7.08 (d, 1H, J=7.2 Hz), 7.02 (s, 1H), 6.90 (d, 1H, J=7.0 Hz), 3.95 (t, 2H, J=6.4 Hz), 3.06 (s, 1H) 1.80-1.75 (m, 2H), 1.48-1.30 (m, 6H), 0.92 (t, 3H, J=6.8 Hz).

Provenance & Evidence