3-Chloro-4-(2-pyridylmethoxy)aniline → tert-Butyl 4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

HRID 195878Notes

Reaction equation

HRID 195878 reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1.[Cl:24][c:25]1[cH:26][c:27]([NH2:28])[cH:29][cH:30][c:31]1[O:32][CH2:33][c:34]1[n:35][cH:36][cH:37][cH:38][cH:39]1>>[c:2]1([NH:28][c:27]2[cH:26][c:25]([Cl:24])[c:31]([O:32][CH2:33][c:34]3[n:35][cH:36][cH:37][cH:38][cH:39]3)[cH:30][cH:29]2)[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1

Participants

3

Reactant 2

HCID 167812123-Chloro-4-(2-pyridylmethoxy)anilineHCID 58116935tert-Butyl 4-chloro-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Product 1

HCID 58116804tert-Butyl 4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Sources & evidence

ORD record
ord-08ad719962164c93a3b402921eae97a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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