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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1958821Generated: October 31, 2026

4-Formylbenzoic acid → rac-N-(3-{4-[5-(4-formyl-phenyl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide

https://huagongshe.com/reaction/1958821

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Formylbenzoic acidHCID 12088—
ReactantHCID 87208794HCID 87208794—
ReactantHCID 178426660HCID 178426660—
Productrac-N-(3-{4-[5-(4-formyl-phenyl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamideHCID 87208910—

Reaction Steps

The title compound was prepared from rac-2-hydroxy-N-{2-hydroxy-3-[4-(N-hydroxycarbamimidoyl)-2,6-dimethyl-phenoxy]-propyl}-acetamide and 4-formyl-benzoic acid in analogy to (rac)-N-(3-{4-[5-(3-formyl-phenyl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide. LC-MS: tR=0.88 min; [M+1]+=426.36.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410151B2
Source datasetuspto-grants-2013_04
ORD IDord-284709f051d04eff8cb859eb38ba4dd2
Source noteuspto-grants-2013_04