HCID 59443036, compound → HCID 59443017, compound

Participants

Reaction Steps

A mixture of the compound obtained in (4) described above (2.8 g) and 2M hydrochloric acid-dichloromethane solution (100 mL) was stirred at room temperature overnight. The reaction mixture was washed successively with a saturated aqueous solution of sodium bicarbonate and brine, dried over sodium sulfate and concentrated in vacuo. The residue is purified by flush chromatography on silica gel (Solvent; petroleum ether/ethyl acetate=25/1) to give the titled compound (1.9 g) as a yellow powder.

Provenance & Evidence