HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1959373Generated: November 4, 2026
Hydrazine hydrate (1:1) → 3-Amino-6-bromopyrazine-2-carbohydrazide
https://huagongshe.com/reaction/1959373
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Methyl 3-Amino-6-bromopyrazine-2-carboxylate | HCID 227251 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Amino-6-bromopyrazine-2-carbohydrazide | HCID 58070256 | 100.4% |
Reaction Steps
A mixture of methyl 3-amino-6-bromo-pyrazine-2-carboxylate (5 g, 21.55 mmol) and hydrazine hydrate (5.397 g, 5.245 mL, 107.8 mmol) were heated to 100° C. for 1.5 hours. Water was added and the product collected by filtration, washed with methanol and dried to give 3-amino-6-bromo-pyrazine-2-carbohydrazide as a yellow solid (5.02 g, 100.4% Yield). MS (ES+) 233.78
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08410112B2 |
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| Source dataset | uspto-grants-2013_04 |
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| ORD ID | ord-2ba0f6b4c36541b3952b58e950d8cc34 |
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| Source note | uspto-grants-2013_04 |
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