HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1959514Generated: October 25, 2026
Methanimidamide, N,N-diphenyl- → 2-(3-Methoxybenzoyl)-3-phenylamino-acrylonitrile
https://huagongshe.com/reaction/1959514
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanimidamide, N,N-diphenyl- | HCID 78296 | — |
| Reactant | 3-(3-Methoxyphenyl)-3-oxopropanenitrile | HCID 584716 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(3-Methoxybenzoyl)-3-phenylamino-acrylonitrile | HCID 67024286 | — |
Reaction Steps
A solution of 3-methoxybenzoylacetonitrile (1.20 g, 68.5 mmol, 1.0 eq) and diphenylformamidine (1.34 g, 68.5 mmol, 1.0 eq) in 25 mL of toluene was stirred at room temperature for 2 h then heated to 100° C. overnight. The solution was cooled and diluted with hexanes. The resulting solid was filtered and dried to provide the desired product. HPLC (4 minute 10-90 gradient) tR 3.05 min; MS m/z 279.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08410160B2 |
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| Source dataset | uspto-grants-2013_04 |
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| ORD ID | ord-a7aa637777b943fcb1713308062b230f |
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| Source note | uspto-grants-2013_04 |
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