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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1959566Generated: October 31, 2026

(3,5-Dichloropyridin-4-yl)methanol → [5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanol

https://huagongshe.com/reaction/1959566

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3,5-Dichloropyridin-4-yl)methanolHCID 17855219—
Reactant5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehydeHCID 44190474—
Product[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanolHCID 44190475—

Reaction Steps

Reduction of the aldehyde group in 5-chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde according to the synthesis of (3,5-dichloro-pyridin-4-yl)-methanol yielded the title compound. MS (m/z): 258.2 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410134B2
Source datasetuspto-grants-2013_04
ORD IDord-753a16db67ed42cd813d66342f9f3e09
Source noteuspto-grants-2013_04