HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-ylmethyl]-isobutyramide → N-(5-Chloro-4-hydroxymethyl-pyridin-3-ylmethyl)-isobutyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-ylmethyl]-isobutyramide | HCID 67077454 | — |
| Reactant | 1-(5-Chloro-4-hydroxymethyl-pyridin-3-yl)-2-methoxy-ethanone | HCID 67077485 | — |
| Product | N-(5-Chloro-4-hydroxymethyl-pyridin-3-ylmethyl)-isobutyramide | HCID 67077216 | — |
Reaction Steps
Deprotection of the tetrahydropyranyl group in N-[5-chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-ylmethyl]-isobutyramide according to the synthesis of 1-(5-chloro-4-hydroxymethyl-pyridin-3-yl)-2-methoxy-ethanone yielded the title compound. MS (m/z): 243.0 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410134B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0f48b58622414ce1aa90dbef6993b809 |
| Source note | uspto-grants-2013_04 |