Thionyl Chloride → HCID 67078088, compound

HRID 1959582Notes

Reaction equation

HRID 1959582 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)[C:7]=1[CH2:8]O.O=S(Cl)[Cl:19].C(N1C=CN=C1SC1C=NC=C(Cl)C=1CCl)CCC>>[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)[C:7]=1[CH2:8][Cl:19]

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 67077290HCID 67077290, compoundHCID 67077520HCID 67077520, compound

Product 1

HCID 67078088HCID 67078088, compound

Procedure

[3-Chloro-5-(pyridin-2-yloxy)-pyridin-4-yl]-methanol (4.24 mg, 0.018 mmol) was chlorinated with SOCl2 according to the synthesis of 3-(1-butyl-1H-imidazol-2-ylsulfanyl)-5-chloro-4-chloromethyl-pyridine to give the title compound. MS (m/z): 255.0 [M+H+].

Sources & evidence

ORD record
ord-a94e87e3a46f40898da525d7feb27897
Source dataset
uspto-grants-2013_04
Patent number
US08410134B2

Reaction notes

Loading…