m-Chloroperbenzoic acid → HCID 67077756, compound

Participants

Reaction Steps

3-Chloroperoxybenzoic acid (mCPBA, 1.32 g, 7.66 mmol) was added to a stirred solution of 3,5-Dichloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine (200 mg, 0.766 mmol) in DCM (5 mL). After stirring for 3 h at RT the solvent was removed in vacuo and the residue was partitioned between DCM (50 mL) and 2 N NaOH solution (50 mL). After extraction of the organic layer with water (50 mL) the organic layer was dried over Na2SO4, filtered, and concentrated in vacuo. The resulting title compound was used for the next reaction without purification. MS (m/z): 278.0 [M+H+].

Provenance & Evidence