HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → tert-Butyl 4-(aminooxy)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Tert-butyl 4-(1,3-dioxoisoindolin-2-yloxy)piperidine-1-carboxylate | HCID 21751544 | — |
| Product | tert-Butyl 4-(aminooxy)piperidine-1-carboxylate | HCID 24729482 | 85% |
Reaction Steps
The title compound was prepared from tert-butyl 4-(1,3-dioxoisoindolin-2-yloxy)piperidine-1-carboxylate and hydrazine monohydrate in 85% yield using the same procedure as described in the synthesis of intermediate G
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410264B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-ab56ce2ff4aa41e380c5c90c96c0c209 |
| Source note | uspto-grants-2013_04 |