HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol, 2-(aminooxy)- → HCID 58190498, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol, 2-(aminooxy)- | HCID 3014186 | — |
| Reactant | 1-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone | HCID 59341802 | — |
| Product | HCID 58190498 | HCID 58190498 | 21% |
Reaction Steps
The title compound was prepared from 1-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone (22.4) and 2-(aminooxy)ethanol in 21% yield using the same procedure as described in the synthesis of example 22. 1H-NMR (400 MHz, CD2Cl2) δ ppm 9.40 (s, 1H), 8.91 (m, 1H), 8.18 (d, 2H), 7.95 (d, 1H), 7.85 (dd, 1H), 7.45 (dd, 1H), 6.13 (s, 2H), 4.46 (t, 2H), 3.97 (t, 2H), 2.39 (s, 3H). LCMS (method A): [MH]+=364, tR=4.28 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410264B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-18ca430bb31e4db49ae5019e2282c1a3 |
| Source note | uspto-grants-2013_04 |