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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1959689Generated: November 1, 2026

Hydroxyamine hydrochloride → HCID 136062024, compound

https://huagongshe.com/reaction/1959689

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
Reactant1-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanoneHCID 59341802—
ProductHCID 136062024HCID 13606202472%

Reaction Steps

The title compound was prepared from 1-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone (22.4) and hydroxylamine hydrochloride in 72% yield using the same procedure as described in the synthesis of example 22. 1H-NMR (400 MHz, DMSO-d6), δ ppm 9.31 (s, 1H), 8.89 (d, 1H), 8.35 (d, 1H), 8.01 (m, 2H), 7.82 (d, 1H), 7.53 (dd, 1H), 6.20 (s, 2H), 2.27 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410264B2
Source datasetuspto-grants-2013_04
ORD IDord-dd90498b17594b1ca1626b01668a8b5a
Source noteuspto-grants-2013_04