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Methanol → HCID 178489420、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 2-Methylbenzothiazole | HCID 8446 | — |
| 反応物 | Hydrazine | HCID 9321 | — |
| 反応物 | Methyl 2-Methoxybenzoate | HCID 61151 | — |
| 触媒 | p-Toluenesulfonic acid | HCID 6101 | — |
| 生成物 | HCID 178489420 | HCID 178489420 | — |
反応手順
The title compound (430 mg) was prepared in four steps starting from 1.49 g (10 mmol) of 2-methylbenzothiazole and 1.66 g (10 mmol) of methyl 2-methoxybenzoate. After the reaction with hydrazine, the addition product was dissolved in methanol and heated to reflux with a catalytic amount of p-TSA (15 mg) for 2 hours to yield the title compound. MS (m/z, ES+): 308 (M+1, 100%). Yield=14%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08410272B2 |
| 出典データセット | uspto-grants-2013_04 |
| ORD ID | ord-c482aeae3ee744f09cf72f88cbd738cb |
| 出典メモ | uspto-grants-2013_04 |