HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine hydrochloride → HCID 46941065, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine hydrochloride | HCID 11198 | — |
| Reactant | HCID 66730410 | HCID 66730410 | — |
| Product | HCID 46941065 | HCID 46941065 | 31.2% |
Reaction Steps
Using N-methyl-8-{4-[2-(tetrahydro-2H-pyran-4-yloxy)ethoxy]phenyl}-1,6-naphthyridine-2-carboxylic acid (300 mg, 0.76 mmol) produced in the synthetic process in Example 9 (9a) and ethylamine hydrochloride (616 mg, 7.61 mmol), the desired title compound (100 mg, yield 31%) was obtained by the same method as in Example 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410273B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-c5c558a1a5f240549f5d8939b547f6c6 |
| Source note | uspto-grants-2013_04 |