反应详情

10 g (58.2 mmol) 1,3-cyclohexane dicarboxylic acid were suspended in acetic anhydride (40 ml) and refluxed during 5 h. The solution was then cooled to room temperature and the solvents were removed in vacuo. The residue was then dissolved in a mixture of heptane (20 ml) and toluene (20 ml) and the solution was cooled to 4° C. The precipitated solid was then collected by filtration and washed with pentane to give 5.9 g of the titled compound as white needles.

1. temperaturerefluxed during 5 h
2. customthe solvents were removed in vacuo
3. dissolutionThe residue was then dissolved in a mixture of heptane (20 ml) and toluene (20 ml)
4. temperaturethe solution was cooled to 4° C
5. filtrationThe precipitated solid was then collected by filtration
6. washwashed with pentane