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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1960067Generated: October 29, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → HCID 178463702, compound

https://huagongshe.com/reaction/1960067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
ReactantHCID 178513852HCID 178513852—
ReactantHCID 178513853HCID 178513853—
ProductHCID 178463702HCID 178463702—

Reaction Steps

4-(Ethyl-{3-[3-(2-fluoro-5-trifluoromethylphenyl)ureido]benzyl}amino)-1H-pyrazole-3-carboxamide is prepared by condensing 1-fluoro-2-isocyanato-4-trifluoromethylbenzene with 4-[(3-aminobenzyl)ethylamino]-1H-pyrazole-3-carboxamide according to the procedure described in Example 34, the latter derivative itself being prepared from 4-[(3-nitrobenzyl)ethylamino]-1H-pyrazole-3-carboxamide according to the procedure also described in Example 34.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410286B2
Source datasetuspto-grants-2013_04
ORD IDord-e7a72a789fdd4d7a92856933916f2959
Source noteuspto-grants-2013_04