Sodium Hydroxide → HCID 44159846, compound

HRID 1960081Notes

Reaction equation

HRID 1960081 reaction equation
C(O)(=O)C(O)=O.[NH2:7][C:8]1[C:13]([C:14]2[O:18][N:17]=[C:16]([CH2:19][OH:20])[CH:15]=2)=[CH:12][CH:11]=[CH:10][N:9]=1.[OH-].[Na+]>O>[NH2:7][C:8]1[C:13]([C:14]2[O:18][N:17]=[C:16]([CH2:19][OH:20])[CH:15]=2)=[CH:12][CH:11]=[CH:10][N:9]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67355904HCID 67355904, compound

Product 1

HCID 44159846HCID 44159846, compoundYield 67.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a mixture of [5-(2-aminopyridin-3-yl)isoxazol-3-yl]methanol oxalate (0.39 g) and water (2 mL) was added 5N aqueous sodium hydroxide (0.5 mL) at room temperature and the precipitated solid was filtered, so as to obtain the title compound (0.18 g) as a white solid.

Workup

  1. filtrationthe precipitated solid was filtered

Sources & evidence

ORD record
ord-4b8d063ff5104814bee9c97d3086378d
Source dataset
uspto-grants-2013_04
Patent number
US08410277B2

Reaction notes

Loading…