Nitric Acid → HCID 58184925, compound

HRID 1960968Notes

Reaction equation

HRID 1960968 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:19])[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:6][CH:5]=1)[CH3:2].[N+:20]([O-])([OH:22])=[O:21]>O>[CH2:1]([O:3][C:4]1[CH:5]=[CH:6][C:7]([C:10](=[O:19])[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:8][C:9]=1[N+:20]([O-:22])=[O:21])[CH3:2]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 19009781-(4-ethoxyphenyl)-2-phenylethane-1,2-dione

Product 1

HCID 58184925HCID 58184925, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
110 °C

Procedure

To 0.5 gram of 1-(4-ethoxyphenyl)-2-phenylethane-1,2-dione prepared in Step 1, was add 10 milliliters of concentrated nitric acid and the resulting mixture was heated to 110° C. for 2 hours. The reaction mixture was cooled and poured into 20 milliliters of water. The precipitate was recrystallized from ethanol to give 1-(4-ethoxy-3-nitrophenyl)-2-phenylethane-1,2-dione. The synthesis is summarized by the equation:

Workup

  1. temperatureThe reaction mixture was cooled
  2. customThe precipitate was recrystallized from ethanol

Sources & evidence

ORD record
ord-2485bf43978e469c968e18b3de1ad024
Source dataset
uspto-grants-2013_04
Patent number
US08411120B2

Reaction notes

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