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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1960974Generated: October 26, 2026

2-(2-Phenylethyl)oxirane → 1-Amino-4-phenylbutan-2-ol

https://huagongshe.com/reaction/1960974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Phenylethyl)oxiraneHCID 135955—
ReactantAmmonia methanolHCID 21705897—
Product1-Amino-4-phenylbutan-2-olHCID 15760987—

Reaction Conditions

Temperature70 °C

Reaction Steps

2-(2-phenylethyl)oxirane (8.0 g, 54 mmol) was placed in a sealed tube with 7N NH3-MeOH (130 mL) and stirred 2 hours at 70° C. followed by concentration to a clear oil (and was used without further purification in the following step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410158B2
Source datasetuspto-grants-2013_04
ORD IDord-78d0743bf7a649f4b8bd702a23f31486
Source noteuspto-grants-2013_04