Potassium Cation → 6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.5]nonane-1-carboxylic acid benzyl ester

HRID 196136Notes

Reaction equation

HRID 196136 reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][C:14]12[CH2:15][NH:16][CH2:17][CH2:18][CH2:19]2.[Cl:20][c:21]1[c:22]2[c:23]([n:24][cH:25][n:26]1)[nH:27][cH:28][cH:29]2.[K+:34].[K+:35].[OH2:36]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][C:14]12[CH2:15][N:16]([c:21]1[c:22]3[c:23]([n:24][cH:25][n:26]1)[nH:27][cH:28][cH:29]3)[CH2:17][CH2:18][CH2:19]2

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-HCID 58293362Benzyl 1,6-diazaspiro[3.5]nonane-1-carboxylate

Product 1

HCID 582933616-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.5]nonane-1-carboxylic acid benzyl ester

Sources & evidence

ORD record
ord-e18db1c076d948de85653aa55155dda6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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