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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961406Generated: October 31, 2026

Morpholine → (S)-Methyl 1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)-6-morpholino-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylate

https://huagongshe.com/reaction/1961406

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant(S)-Methyl 1-(4-chloro-6-(5-cyclopropyl-1H-pyrazol-3-ylamino)-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylateHCID 59436414—
Product(S)-Methyl 1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)-6-morpholino-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylateHCID 59436321—

Reaction Steps

Compound 106F was prepared from morpholine and 106E as described for 1: LC/MS [M+H]+: 457; Ret time (Method F): 2.97 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415340B2
Source datasetuspto-grants-2013_04
ORD IDord-63c9ed5e50a748bdbdff54309fd351f5
Source noteuspto-grants-2013_04