Hydrochloric Acid → HCID 46908483, compound

Participants

Reaction Steps

N-(4-(1,4-Dioxaspiro[4.5]decan-8-yl)benzyl)-2-methyl-1,8-naphthyridine-3-carboxamide (35.9 mg, 0.086 mmol) was dissolved in THF (1 ml). Aqueous HCl (1 ml, 1M) was added and the reaction was stirred at room temp for 18 hours. Reaction was then diluted with NaHCO3 (10 ml, sat aq) and extracted with EtOAc (2*15 ml). Combined organics were dried over MgSO4 and evaporated to give 25 mg (88%) of title compound as a pale mass.

Provenance & Evidence