Cyclohexanecarboxylic acid → 6-Cyclohexyl-3-pyridinecarboxaldehyde

HRID 1961462Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][OH:8])[CH:2]=1.[CH:9]1(C(O)=O)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.C(C1C=CC(C=O)=CN=1)(C)(C)C>>[CH:9]1([C:6]2[CH:5]=[CH:4][C:3]([CH:7]=[O:8])=[CH:2][N:1]=2)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

Reactant 3

HCID 7413Cyclohexanecarboxylic acid

HCID 75103-Pyridinemethanol

HCID 112406656-tert-Butyl-3-formylpyridine

Product 1

HCID 824044216-Cyclohexyl-3-pyridinecarboxaldehydeYield 6%

Procedure

This compound was synthesized in 6% yield from 3-pyridine methanol and cyclohexane carboxylic acid using the same procedure as for 6-tert-butylnicotinaldehyde.

Sources & evidence

ORD record: ord-aaa25ad5b3f5475ba7f3e9dcb0ede2cc
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08415333B2

Reaction notes

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