Cyclopentanecarboxylic acid → 1237977-52-4

HRID 1961485Notes

Reaction equation

[Cl:1][C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH:10]1(C(O)=O)[CH2:14][CH2:13][CH2:12][CH2:11]1.C(C1C=CC(C#N)=C(Cl)N=1)(C)(C)C>>[Cl:1][C:2]1[N:9]=[C:8]([CH:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

Reactant 3

HCID 18840Cyclopentanecarboxylic acid

HCID 810792-Chloronicotinonitrile

HCID 532788766-Tert-butyl-2-chloropyridine-3-carbonitrile

Product 1

HCID 626317451237977-52-4Yield 41%

Procedure

This compound was synthesized in 41% yield from 2-chloronicotinonitrile and cyclopentanecarboxylic acid using the same procedure as for 6-tert-butyl-2-chloronicotinonitrile.

Sources & evidence

ORD record: ord-55ae268683504cc79a02656820820bf1
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08415333B2

Reaction notes

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