HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-phenyl-1H-pyrazole-4-carbonitrile → 3-({4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-phenyl-1H-pyrazole-4-carbonitrile | HCID 2774249 | — |
| Reactant | 4-(4-Iodobenzyl)thiomorpholine 1,1-dioxide | HCID 58285156 | — |
| Product | 3-({4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrile | HCID 67253548 | — |
Reaction Steps
3-({4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrile was prepared according to the general procedure in Example 11 Step 1 using 3-amino-1-phenyl-1H-pyrazole-4-carbonitrile (100 mg, 0.543 mmol) and 4-(4-iodobenzyl)thiomorpholine 1,1-dioxide (191 mg, 0.543 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415346B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-32f7965d71354b06a825adef73154c95 |
| Source note | uspto-grants-2013_04 |