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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961521Generated: October 25, 2026

(+)-Lactose → 1-[4-(1-Hydroxyethyl)phenyl]-3-[[4-(methylsulfonyl)phenyl]amino]-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/1961521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+)-LactoseHCID 440995—
Reactant3-[[4-(Methylsulfonyl)phenyl]amino]-1-phenyl-1H-pyrazole-4-carboxamideHCID 44626207—
Product1-[4-(1-Hydroxyethyl)phenyl]-3-[[4-(methylsulfonyl)phenyl]amino]-1H-pyrazole-4-carboxamideHCID 44625231—

Reaction Steps

As a specific embodiment of this invention, 100 mg of 3-{[4-(methylsulfonyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carboxamide is formulated with sufficient finely divided lactose to provide a total amount of 580 to 590 mg to fill a size 0, hard-gelatin capsule.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415346B2
Source datasetuspto-grants-2013_04
ORD IDord-c8a7cb55c6dd4f1c9d7742ca928da7be
Source noteuspto-grants-2013_04