HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 66627373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 57918176 | HCID 57918176 | — |
| Reactant | HCID 66627829 | HCID 66627829 | — |
| Product | HCID 66627373 | HCID 66627373 | 73.4% |
Reaction Steps
According to the synthesis of Trans-2-(tert-Butoxycarbonylamino-methyl)-cyclopropanecarboxylic acid ethyl ester (intermediate L, example 43), the title compound was prepared from Trans-2-[tert-Butoxycarbonylamino-(toluene-4-sulfonyl)-methyl]-cyclobutanecarboxylic acid methyl ester (17.7 g, 44.53 mmol), sodium borohydride (3.3 g, 83.74 mmol) and 8.2 g, (33.7 mmol, 73.4% yield) was obtained. MS (m/e): 244.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415350B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-bab5f4c31ad143da82c9311e5da3bfdf |
| Source note | uspto-grants-2013_04 |