Thiophene-3-boronic acid → 2-(Thien-3-yl)-5-fluorophenol

HRID 196164Notes

Reaction equation

HRID 196164 reaction equation
[Br:18][c:19]1[cH:20][c:21]([F:22])[c:23]([F:24])[cH:25][c:26]1[OH:27].[Br:1][c:2]1[c:3]([OH:9])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[s:10]1[cH:11][c:12]([B:15]([OH:16])[OH:17])[cH:13][cH:14]1.[s:28]1[cH:29][cH:30][cH:31][c:32]1[B:33]([OH:34])[OH:35]>>[c:2]1(-[c:12]2[cH:11][s:10][cH:14][cH:13]2)[c:3]([OH:9])[cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 581760Thiophene-3-boronic acidHCID 27246002-Bromo-5-fluorophenolHCID 27339602-Thiopheneboronic acidHCID 27362882-Bromo-4,5-difluorophenol

Product 1

HCID 227234392-(Thien-3-yl)-5-fluorophenol

Sources & evidence

ORD record
ord-6c75cc7a144e499bb010e2b18f21c46d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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