Thiophene → HCID 58032828, compound

HRID 1961658Notes

Reaction equation

HRID 1961658 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[C:6]([O:10][C:11]([N:13]1[CH2:18][CH2:17][CH:16]([CH:19]=[O:20])[CH2:15][CH2:14]1)=[O:12])([CH3:9])([CH3:8])[CH3:7]>>[C:6]([O:10][C:11]([N:13]1[CH2:18][CH2:17][CH:16]([CH:19]([OH:20])[C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)[CH2:15][CH2:14]1)=[O:12])([CH3:9])([CH3:8])[CH3:7]

Participants

3

Reactant 2

HCID 8030ThiopheneHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylate

Product 1

HCID 58032828HCID 58032828, compound

Procedure

From thiophene (130 mg) and 4-formyl-piperidine-1-carboxylic acid tert-butyl ester (300 mg) by procedure D. Yield: 167 mg (40%). Yellow oil. MS (m/z): 298.1 ([M+H]+).

Sources & evidence

ORD record
ord-d5c2bb9e687d45c78df8c32246e7499b
Source dataset
uspto-grants-2013_04
Patent number
US08415350B2

Reaction notes

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