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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961665Generated: October 30, 2026

(5-Chloro-thiophen-2-yl)-piperidin-4-yl-methanone hydrochloride → HCID 178453901, compound

https://huagongshe.com/reaction/1961665

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Chloro-thiophen-2-yl)-piperidin-4-yl-methanone hydrochlorideHCID 66625802—
ReactantHCID 178453924HCID 178453924—
ProductHCID 178453901HCID 178453901—

Reaction Steps

From (5-chloro-thiophen-2-yl)-piperidin-4-yl-methanone hydrochloride (585 mg) and [trans-4-(2-oxo-ethyl)-cyclohexyl]-carbamic acid tert-butyl ester (intermediate C, 530 mg) by procedure A.2. Yield: 513 mg (51%). Light yellow solid. MS (m/z): 455.2 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415350B2
Source datasetuspto-grants-2013_04
ORD IDord-42eaf509703b49de95fa1bd22afa0a20
Source noteuspto-grants-2013_04