Methyl DL-prolinate → Methyl 1-[2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]phenyl]sulfonylpyrrolidine-2-carboxylate
Reaction equation
[CH3:33][O:34][C:35](=[O:36])[CH:37]1[NH:38][CH2:39][CH2:40][CH2:41]1.[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7](-[c:23]3[c:24]([S:29](=[O:30])(=[O:31])[Cl:32])[cH:25][cH:26][cH:27][cH:28]3)[cH:8][c:9]2[c:10]([C:12](=[O:13])[N:14]2[CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[CH2:22]2)[n:11]1>>[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7](-[c:23]3[c:24]([S:29](=[O:30])(=[O:31])[N:38]4[CH:37]([C:35]([O:34][CH3:33])=[O:36])[CH2:41][CH2:40][CH2:39]4)[cH:25][cH:26][cH:27][cH:28]3)[cH:8][c:9]2[c:10]([C:12](=[O:13])[N:14]2[CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[CH2:22]2)[n:11]1Participants
3
Sources & evidence
- ORD record
- ord-4222b2387a4942d3b0b463e5f045fdbc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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