HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclopentylpropionyl chloride → HCID 44819651, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclopentylpropionyl chloride | HCID 66039 | — |
| Reactant | Ribociclib | HCID 44631912 | — |
| Product | HCID 44819651 | HCID 44819651 | 44.4% |
Reaction Steps
Following General Procedure G, 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (100 mg, 0.230 mmol) and 3-cyclopentyl propionyl chloride (39 mL, 0.690 mmol) gave 7-cyclopentyl-2-{5-[4-(3-cyclopentyl-propionyl)-piperazin-1-yl]-pyridin-2-ylamino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (57 mg, 44%). MS(ESI) m/z 559.4 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415355B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-cafc99d6e10a413ab878c8169473569b |
| Source note | uspto-grants-2013_04 |