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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196227Generated: October 27, 2026

Trifluoroacetic acid → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (4-methanesulfonyl-phenyl)-amide

https://huagongshe.com/reaction/196227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantDiphenylphosphinic chlorideHCID 73910—
Reactant4-(Methylsulfonyl)anilineHCID 79617—
ReactantDiisopropylethylamineHCID 81531—
Reactantrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acidHCID 66625245—
Productrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (4-methanesulfonyl-phenyl)-amideHCID 75985660—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-2170acca222b4390ad5fc932d4938b7d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)